| Date | Location | Result | |
| 11/20/21 | Buies Creek, NC | Campbell 3, WINTHROP 0 (26-24,25-21,25-17) | Box score |
| 11/19/21 | Buies Creek, NC | WINTHROP 3, Presbyterian 1 (25-18,23-25,25-15,25-22) | Box score |
| 11/12/21 | Radford, VA | WINTHROP 3, Radford 0 (25-17,25-18,25-23) | Box score |
| 11/10/21 | Rock Hill, SC | WINTHROP 3, Gardner-Webb 0 (25-19,25-22,25-16) | Box score |
| 11/06/21 | Clinton, SC | WINTHROP 3, Presbyterian 1 (25-20,25-8,21-25,25-15) | Box score |
| 11/05/21 | North Charleston, SC | WINTHROP 3, Charleston So. 1 (25-23,21-25,25-10,25-20) | Box score |
| 10/30/21 | Rock Hill, SC | WINTHROP 3, USC Upstate 0 (25-19,25-18,25-8) | Box score |
| 10/29/21 | Rock Hill, SC | WINTHROP 3, UNC Asheville 0 (25-19,25-14,25-12) | Box score |
| 10/22/21 | High Point, NC | High Point 3, WINTHROP 0 (25-21,25-20,25-18) | Box score |
| 10/19/21 | Rock Hill, SC | N.C. A&T 3, WINTHROP 2 (21-25,25-13,25-14,20-25,15-10) | Box score |
| 10/16/21 | Rock Hill, SC | WINTHROP 3, Hampton 0 (25-17,25-12,25-10) | Box score |
| 10/12/21 | Buies Creek, NC | Campbell 3, WINTHROP 1 (25-14,23-25,25-16,25-21) | Box score |
| 10/09/21 | Asheville, NC | WINTHROP 3, UNC Asheville 1 (25-16,25-14,14-25,25-14) | Box score |
| 10/08/21 | Spartanburg, SC | USC Upstate 3, WINTHROP 1 (25-22,25-22,22-25,25-21) | Box score |
| Oct 02, 2021 | Rock Hill, SC | WINTHROP 3, CHSO 0 (25-21,25-21,25-16) | Box score |
| 10/01/21 | Rock Hill, SC | WINTHROP 3, Presbyterian 2 (21-25,25-12,28-30,25-16,15-9) | Box score |
| 09/25/21 | Rock Hill, SC | WINTHROP 3, Radford 0 (25-16,25-22,25-23) | Box score |
| 09/24/21 | Boiling Springs, NC | WINTHROP 3, Gardner-Webb 0 (25-21,25-16,25-23) | Box score |
| 09/19/21 | Rock Hill, SC | WINTHROP 3, Charlotte 0 (25-23,25-23,25-20) | Box score |
| 09/16/21 | Rock Hill, SC | South Carolina 3, WINTHROP 0 (25-18,25-18,25-21) | Box score |
| Sep 11, 2021 | Rock Hill, SC | ETSU 3, WINTHROP 0 (25-18,25-17,25-23) | Box score |
| Sep 10, 2021 | Rock Hill, S.C. | WINTHROP 3, ETSU 0 (25-20,25-22,25-18) | Box score |
| 09/04/21 | Charlottesville, VA | WINTHROP 3, Virginia 0 (25-18,26-20,25-18) | Box score |
| 09/03/21 | WINTHROP 3, William & Mary 1 (23-25,25-16,25-16,25-20) | Box score | |
| 09/03/21 | Charlottesville, VA | WINTHROP 3, Akron 0 (25-18,26-24,25-23) | Box score |
| 08/28/21 | Athens, GA | Morehead St. 3, WINTHROP 1 (26-24,25-14,22-25,25-18) | Box score |
| 08/28/21 | Athens, GA | Georgia 3, WINTHROP 0 (25-23,25-21,25-19) | Box score |
| 08/27/21 | Athens, GA | Pepperdine 3, WINTHROP 1 (25-18,18-25,25-14,25-14) | Box score |