| Date | Location | Result | |
| 3/16/10 | University of Dayton Arena | Arkansas-Pine Bluff 61, Winthrop 44 | Box score |
| 03-04-10 | Kimbel Arena--Conway, SC | Winthrop 61, Radford 46 | Box score |
| 03-06-10 | Conway, S.C. (Kimbel Arena) | Winthrop 64, Coastal Carolina 53 | Box score |
| 3-2-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 80, LIBERTY 72 | Box score |
| 02-27-10 | Radford, Va. -- Dedmon Center | Radford 54, Winthrop 52 | Box score |
| 02-25-10 | Millis Center--High Point, NC | High Point 71, Winthrop 66 | Box score |
| 02-23-09 | Winthrop Coliseum--Rock Hill, SC | Winthrop 68, UNC Asheville 65 | Box score |
| 02-20-10 | McBrayer Arena--Richmond, KY | Eastern Kentucky 77, Winthrop 57 | Box score |
| 02-16-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 69, Gardner-Webb 64 | Box score |
| 02-13-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 66, Presbyterian College 53 | Box score |
| 02-06-10 | Cameron Hall--Lexington, VA | Winthrop 87, VMI 83 | Box score |
| 02-04-10 | Vines Center--Lynchburg, VA | Winthrop 67, Liberty 43 | Box score |
| 01-30-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 67, Coastal Carolina 64 | Box score |
| 01-28-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 55, Charleston Southern 53 | Box score |
| 01-23-10 | Paul Porter Arena--Boiling Springs, NC | Winthrop 65, Gardner-Webb 45 | Box score |
| 01-21-10 | Justice Center--Asheville, NC | UNC Asheville 66, Winthrop 53 | Box score |
| 01-16-10 | Clinton, S.C. Templeton Center | WU 56, Presbyterian College 42 | Box score |
| 01-09-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 65, Liberty 62 | Box score |
| 01-07-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 96, VMI 63 | Box score |
| 01-04-10 | CSU Field House--Charleston, S.C. | Charleston Southern 57, Winthrop 54 | Box score |
| 01-02-10 | Kimbel Arena--Conway, SC | Coastal Carolina 57, Winthrop 47 | Box score |
| 12-29-09 | RBC Center--Raleigh, NC | North Carolina State 68, Winthrop 52 | Box score |
| 12-22-09 | Fifth Third Arena (Cincinnati, OH) | Cincinnati 74, Winthrop University 57 | Box score |
| 12-20-09 | Winthrop Coliseum--Rock Hill, SC | Charlotte 57, Winthrop 47 | Box score |
| 12-16-09 | Spartanburg, S.C. (Hodge Center) | Winthrop 62, USC Upstate 53 | Box score |
| 12-12-09 | Winthrop Coliseum--Rock Hill, SC | Winthrop 64, Barton 51 | Box score |
| 12-05-09 | Winthrop Coliseum--Rock Hill, SC | Winthrop 82, High Point 68 | Box score |
| 12-03-09 | Winthrop Coliseum--Rock Hill, SC | Radford 61, Winthrop 59 | Box score |
| 11-30-09 | Boone, N.C. (Holmes Center) | Appalachian State 70, Winthrop 51 | Box score |
| 11-23-09 | Clemson, SC (Littlejohn Coliseum) | Clemson 102, Winthrop 66 | Box score |
| 11-21-09 | Winthrop Coliseum--Rock Hill, SC | Winthrop 49, USC Upstate 46 | Box score |
| 11-17-09 | Carolina First Arena | College of Charleston 69, Winthrop 57 | Box score |
| 11-14-09 | Winthrop Coliseum--Rock Hill, SC | Winthrop 57, Limestone 55 | Box score |