| Date | Location | Result | |
| 3-12-10 | Millis Center (High Point, N.C.) | High Point 68, Winthrop 65 | Box score |
| 03/08/10 | Charleston, S.C. (CSU Field House) | CSU 66, Winthrop 62 | Box score |
| 03-05-10 | Asheville, N.C./Justice Center | Winthrop 73, UNC Asheville 66 | Box score |
| 3-1-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 47, Coastal Carolina 39 | Box score |
| 2-27-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 56, High Point 50 | Box score |
| 02-22-10 | Boiling Springs, N.C.(Paul Porter Arena) | GWU 57, Winthrop 39 | Box score |
| 2-15-10 | Winthrop Coliseum--Rock Hill, SC | Liberty 52, Winthrop 18 | Box score |
| 2-13-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 56, Radford 52 | Box score |
| 2-9-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 57, NCCU 39 | Box score |
| 02/06/10 | Templeton Center (Clinton, S.C.) | Presbyterian College 48, WINTHROP 43 | Box score |
| 2-1-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 58, CSU 48 | Box score |
| 1-30-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 44, UNC Asheville 38 | Box score |
| 1/26/10 | Farmville, Virginia (Willett Hall) | Longwood 62, Winthrop 51 | Box score |
| 1-23-10 | Winthrop Coliseum--Rock Hill, SC | GWU 85, Winthrop 62 | Box score |
| 01-18-10 | Conway, S.C. (Kimbel Arena) | Coastal Carolina 59, Winthrop 57 | Box score |
| 1-16-10 | Millis Center (High Point, N.C.) | High Point 69, Winthrop 60 | Box score |
| 01/11/10 | Dedmon Center (Radford, Va.) | Radford 57, Winthrop 48 | Box score |
| 01-09-10 | Lynchburg, Va. (Vines Center) | Liberty 67, Winthrop 38 | Box score |
| 1-2-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 57, PC 40 | Box score |
| 12-30-09 | Winthrop Coliseum--Rock Hill, SC | MERCER 58, WINTHROP 49 | Box score |
| 12/21/09 | Buies Creek, N.C. (Gore Arena/Pope Ctr) | Winthrop 66, Campbell 60 | Box score |
| 12/19/09 | Raleigh, N.C. (Reynolds Coliseum) | NC State 66, Winthrop 53 | Box score |
| 12-15-09 | Lifepointe Community Center-Fort Mill,SC | VCU 65, WINTHROP 51 | Box score |
| 12-12-09 | Winthrop Coliseum--Rock Hill, SC | WINTHROP 73, ASU 50 | Box score |
| 12-5-09 | Winthrop Coliseum--Rock Hill, SC | WINTHROP 62, USCAW 53 | Box score |
| 11/28/09 | Worthington Arena - Bozeman, Montana | Montana State 60, Winthrop 41 | Box score |
| 11/27/09 | Worthington Arena - Bozeman, Montana | Winthrop 72, Utah Valley 59 | Box score |
| 11/21/09 | Towson Center (Towson, Md.) | Chicago State 45, WINTHROP 41 | Box score |
| 11/20/09 | Towson Center (Towson, Md.) | Towson University 56, Winthrop 46 | Box score |
| 11-17-09 | Winthrop Coliseum--Rock Hill, SC | WINTHROP 58, COKERWBB 47 | Box score |
| 11/13/09 | Alexander Memorial Coliseum, Atlanta, GA | Georgia Tech 63, Winthrop 30 | Box score |