| Date | Location | Result | |
| 11-19-10 | Rock Hill, SC | Liberty 3, Winthrop 2 (21-25,17-25,25-15,25-22,17-15) | Box score |
| 11-18-10 | Rock Hill, SC | Winthrop 3, Coastal Carolina 0 (25-17,25-22,25-23) | Box score |
| Nov 13, 2010 | Rock Hill, SC | Winthrop 3, Gardner-Webb 0 (25-23,25-16,25-13) | Box score |
| Nov 10, 2010 | Rock Hill, SC | Winthrop 3, Presbyterian College 0 (25-19,25-22,25-21) | Box score |
| Nov 05, 2010 | Asheville, N.C. | UNC Asheville 3, Winthrop 2 (25-22,22-25,22-25,25-23,15-13) | Box score |
| Oct 30, 2010 | Rock Hill, SC | Winthrop 3, Liberty 0 (28-26,25-18,25-20) | Box score |
| Oct 26, 2010 | Conway, S.C. | Coastal Carolina 3, Winthrop 1 (25-18,22-25,25-16,25-21) | Box score |
| Oct 23, 2010 | High Point, NC | High Point 3, Winthrop 0 (25-12,29-27,25-18) | Box score |
| Oct 22, 2010 | Radford, Va. | Radford 3, Winthrop 2 (15-25,25-16,25-22,18-25,15-12) | Box score |
| Oct 19, 2010 | Rock Hill, SC | Winthrop 3, Charleston Southern 0 (25-15,25-16,25-19) | Box score |
| Oct 16, 2010 | Clinton, SC | Presbyterian College 3, Winthrop 2 (18-25,25-23,25-18,20-25,15-7) | Box score |
| Oct 15, 2010 | Boiling Springs, NC | Winthrop 3, Gardner-Webb 2 (20-25,22-25,25-17,25-21,15-13) | Box score |
| Oct 9, 2010 | Rock Hill, SC | Winthrop 3, UNC Asheville 1 (25-21,25-22,21-25,26-24) | Box score |
| Oct 05, 2010 | Rock Hill, SC | Winthrop 3, Coastal Carolina 0 (26-24,25-20,25-19) | Box score |
| Oct. 1, 2010 | Lynchburg, Va. | Winthrop 3, Liberty 1 (28-26,17-25,28-26,26-24) | Box score |
| Sep 28, 2010 | Charleston, S.C. | Winthrop 3, Charleston Southern 0 (25-19,27-25,25-23) | Box score |
| Sep 25, 2010 | Rock Hill, SC | Winthrop 3, Radford 0 (25-20,25-16,25-23) | Box score |
| Sep 24, 2010 | Rock Hill, SC | High Point 3, Winthrop 2 (30-28,21-25,16-25,25-20,15-11) | Box score |
| Sep 18, 2010 | Statesboro, Ga. | East Tennessee State 3, Winthrop 2 (25-14,24-26,18-25,25-19,15-13) | Box score |
| Sep 17, 2010 | Statesboro, Ga. | Georgia Southern 3, Winthrop 0 (25-20,25-20,25-23) | Box score |
| Sep 17, 2010 | Statesboro, Ga. | Winthrop 3, South Alabama 1 (25-13,25-22,23-25,25-19) | Box score |
| Sep 11, 2010 | Lawrence, Kan. | Northern Iowa 3, Winthrop 0 (25-19,25-19,25-12) | Box score |
| Sep 10, 2010 | Lawrence, Kan. | Arkansas Little Rock 3, Winthrop 1 (25-13,21-25,25-22,25-23) | Box score |
| Sep 10, 2010 | Lawrence, Kan. | Kansas 3, Winthrop 1 (25-12,25-21,27-29,25-20) | Box score |
| Sep. 4, 2010 | Rock Hill, SC | Winthrop 3, South Carolina 1 (21-25,25-22,25-22,25-23) | Box score |
| Sep. 4, 2010 | Rock Hill, SC | Clemson 3, Winthrop 0 (30-28,25-16,25-17) | Box score |
| Sep. 3, 2010 | Rock Hill, SC | Coll. of Charleston 3, Winthrop 2 (19-25,25-22,16-25,25-18,15-8) | Box score |
| Aug 28, 2010 | Williamsburg, Va. | William and Mary 3, Winthrop 2 (25-23,25-18,25-27,18-25,15-13) | Box score |
| Aug 27, 2010 | Williamsburg, Va. | Winthrop 3, Seton Hall 2 (25-19,25-17,26-28,26-28,15-11) | Box score |
| Aug 27, 2010 | Williamsburg, Va. | Wisconsin 3, Winthrop 0 (25-14,25-22,25-14) | Box score |